Organ support & nutrition

Functional outcomes among the survivors of veno-venous extracorporeal membrane oxygenation during the COVID-19 pandemic: a historical cohort study

Can J AnaesthPublished Historical cohort study

Authors' conclusion

Patients who required VV-ECMO experienced significant functional disability, pain, cognitive challenges, mental health problems, and lower quality of life approximately two years after discharge.

Study context

Population
Survivors who required veno-venous extracorporeal membrane oxygenation (VV-ECMO) for respiratory failure during the COVID-19 pandemic22 (85%) COVID-19
Participants
26 survivors
Outcome
Postdischarge psychological and functional outcomes (disability: WHODAS 2.0, mRS; quality of life; cognition; depression; PTSD symptoms)
Follow-up
Median 22 [IQR 17-23] months after ECMO separation
Methodological detailstelephone interviews, descriptive statistics
  • Telephone interviews
  • Descriptive statistics

Main finding

As reported in the abstract

Disability (WHODAS 2.0 score) · median 22 [17-23] months after ECMO separation

Median [IQR] WHODAS 2.0 score; highest disability in mobility and participation domains

26

15–30

Observational data: associations, not effects.

Original publication

Functional outcomes among the survivors of veno-venous extracorporeal membrane oxygenation during the COVID-19 pandemic: a historical cohort study. Can J Anaesth. Published 29 May 2025. doi:10.1007/s12630-025-02965-9

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