Perioperative medicine & outcomes

Glucocorticoids for Patients With Acute Decompensated Heart Failure: A Protocol for a Systematic Review With Meta‐Analysis and Trial Sequential Analysis

Acta Anaesthesiol ScandPublished Protocol for a systematic review and meta-analysis of randomised trials

Study context

Population
Patients hospitalized with acute decompensated heart failure (ADHF)
Planned comparison
Glucocorticoids vs Control
Primary endpoint
All-cause mortality
Methodological detailstrial sequential analysis, Cochrane Risk of Bias tool-version 2, Grading of Recommendations, Assessment, Development and Evaluations (GRADE), Search planned to begin April 2026 (Medline, Embase, CENTRAL, LILACS, Web of Science)
  • Trial sequential analysis
  • Cochrane Risk of Bias tool-version 2
  • GRADE
  • Search planned to begin April 2026 (Medline, Embase, CENTRAL, LILACS, Web of Science)

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Glucocorticoids for Patients With Acute Decompensated Heart Failure: A Protocol for a Systematic Review With Meta‐Analysis and Trial Sequential Analysis. Acta Anaesthesiol Scand. Published 22 May 2026. doi:10.1111/aas.70264

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