Glucose Management in the Intensive Care Unit (ICU) : The Bi‐Centre GEM ‐ ICU Cohort Study
Authors' conclusion
In this Danish bi-centre cohort of acutely admitted ICU patients, hypoglycaemia was uncommon and severe hypoglycaemia was rare, whereas hyperglycaemia occurred in almost every second patient.
Study context
- Population
- Acutely admitted adults at two Danish intensive care units (ICUs)285 with ≥1 glucose measurement
- Participants
- 300 participants
- Outcome
- Hypoglycaemia (< 4 mmol/L)
- Follow-up
- During ICU stay
Methodological detailsbi-centre
- Bi-centre
Main finding
As reported in the abstract
Hypoglycaemia (< 4 mmol/L) during ICU stay
Hypoglycaemia observed
21 (7.4%; 95% CI 4.6-11.0) (patients, %; 95% CI)
Observational data: associations, not effects.
Secondary outcomes
Severe hypoglycaemia (< 2.3 mmol/L)
- Severe hypoglycaemia observed
- 3 (1.1%; 95% CI 0.2-3.0) (patients, %; 95% CI)
Hyperglycaemia (> 10 mmol/L)
- Hyperglycaemia observed
- 186 (65.3%; 95% CI 59.4-70.8) (patients, %; 95% CI)
Mortality · 30 days
- Mortality at 30 days
- 24.3% (95% CI 19.6-29.6) (%; 95% CI)
Days alive without life support (DAWOLS) · 30 days
- Median DAWOLS
- 27 days (95% CI 26-28; IQR 8-30) (days; 95% CI; IQR)
Days alive out of hospital (DAOH) · 30 days
- Median DAOH
- 9 days (95% CI 3-14; IQR 0-21) (days; 95% CI; IQR)
Original publication
Glucose Management in the ICU : The Bi‐Centre GEM ‐ ICU Cohort Study. Acta Anaesthesiol Scand. Published 19 February 2026. doi:10.
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