Glycaemic control for patients with severe acute brain injury: Protocol for a systematic review

Acta Anaesthesiol ScandPublished Protocol for a systematic review and meta-analysis

Study context

Population
Adults with severe acute brain injury
Planned comparison
Restrictive vs liberal glucose control
Primary endpoint
All-cause mortality, functional outcome and health-related quality of life
Methodological detailstrial sequential analysis, Grading of Recommendations, Assessment, Development and Evaluations (GRADE), Risk of bias by Cochrane tool; evidence quality by GRADE, RCTs comparing levels of glucose control; observational studies included to address potential harms
  • Trial sequential analysis
  • GRADE
  • Risk of bias by Cochrane tool; evidence quality by GRADE
  • RCTs comparing levels of glucose control; observational studies included to address potential harms

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Glycaemic control for patients with severe acute brain injury: Protocol for a systematic review. Acta Anaesthesiol Scand. Published 12 November 2022. doi:10.1111/aas.14166

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