Perioperative medicine & outcomes

Glycemic profile and quality of recovery after emergency abdominal surgery–A prospective explorative cohort study

Acta Anaesthesiol ScandPublished Prospective cohort study

Authors' conclusion

Alterations in the glycemic profile are frequent and prolonged during the first postoperative month after major surgery probably due to peripheral insulin resistance.

Study context

Population
Nondiabetic adults after acute, major abdominal surgery27 completed per protocol
Outcome
Association between 30-day glycemic profile metrics (continuous glucose measurement) and patient-reported recovery (Quality of Recovery-15)
Follow-up
POD 10, 20 and 30
Methodological detailsexplorative
  • Explorative

Main finding

As reported in the abstract

Recovery score vs coefficient of variation of glucose · During 30 days of follow-up

Recovery score estimate, coefficient of variation measured 3 days before assessment (p < .001)

−1.52

Recovery score estimate, coefficient of variation measured 5 days before assessment (p = .006)

−0.92

Observational data: associations, not effects.

Further findings

Hyperglycemic event (>200 mg/dl) · first three postoperative days

Patients with hyperglycemic event: 18 of 27
67%

Coefficient of variation vs reference period (days 26-30)

Significantly increased during all time intervals

Original publication

Glycemic profile and quality of recovery after emergency abdominal surgery–A prospective explorative cohort study. Acta Anaesthesiol Scand. Published 5 January 2023. doi:10.1111/aas.14182

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