Safety, quality & education

Grading of Recommendations Assessment, Development and Evaluation (GRADE) pearls and pitfalls—Part 2: Clinical practice guidelines

Acta Anaesthesiol ScandPublished Methodological overview

Authors' conclusion

This overview aims to help developers, assessors and users of clinical practice guidelines understand how trustworthy, high-quality guidelines are developed using the GRADE approach.

Study context

Population
Clinicians and researchers who are, or plan to be, involved in the development or assessment of clinical practice guidelines
Outcome
Use of the GRADE approach in clinical practice guidelines

Main finding

As reported in the abstract

  • Guideline endorsement and adaptation
  • Guideline panels and sponsors
  • Conflicts of interest
  • Guideline questions and outcome prioritisation
  • Systematic review creation, updating and re-use
  • Rating the overall certainty of evidence
  • Development of recommendations and implications
  • Peer review, publication, implementation and updating of guidelines

Original publication

GRADE pearls and pitfalls—Part 2: Clinical practice guidelines. Acta Anaesthesiol Scand. Published 21 February 2024. doi:10.1111/aas.14384

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