Perioperative medicine & outcomes
Haemodynamic and respiratory perioperative outcomes for open versus robot‐assisted radical cystectomy: A double‐blinded, randomised trial
Authors' conclusion
A prolonged Trendelenburg position and CO2 pneumoperitoneum was well-tolerated during iRARC, and immediate postoperative recovery was similar for ORC and iRARC patients.
Study context
- Population
- Bladder cancer patients undergoing radical cystectomy
- Participants
- 50 patients
- Comparison
- Open radical cystectomy (RC) vs robot-assisted RC with intracorporal urinary diversion
- Open RC (ORC)n = 25reference
- iRARCn = 25
- Primary endpoint
- Immediate postoperative recovery (standardised PACU Discharge Criteria score)
Methodological detailspredefined sub-analysis, single-centre, double-blinded, All patients underwent the allocated treatment, Patients, post-anaesthesia care unit (PACU) staff and ward personnel blinded to surgical technique
- Predefined sub-analysis
- Single-centre
- Double-blinded
- All patients underwent the allocated treatment
- Patients, PACU staff and ward personnel blinded to surgical technique
Primary result
As reported in the abstract
Total PACU-DC score
- Total PACU Discharge Criteria (PACU-DC) score highest 6 h postoperatively
- iRARC vs ORC: P = 0.80
Secondary outcomes
Respiration and arterial O2 saturation scores
- Mean scores below 1 (out of 3) in both groups throughout PACU stay
Intraoperative recordings
- iRARC significantly (clinically acceptable) higher maximum airway pressure and arterial BP, lower minimum pH
Analgesia
- ORC received significantly more opioids after extubation but marginally less analgesics in PACU vs iRARC
Original publication
Haemodynamic and respiratory perioperative outcomes for open versus robot‐assisted radical cystectomy: A double‐blinded, randomised trial. Acta Anaesthesiol Scand. Published 5 January 2023. doi:10.
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