Pediatric anesthesia & critical care
Health Care Resource Use and Costs After Hospitalization With Multiple Organ Dysfunction in Children
Authors' conclusion
In this cohort study of nearly 1.7 million children, survivors of MOD accrued substantial ongoing health care resource use and cost burden after the index hospitalization.
Study context
- Population
- Infants (<1 year) and children (1–18 years) with an index hospitalization 2005–2018, US Optum Clinformatics claims databaseweighted sample
- Participants
- 9,671 vs 1,691,793
- Exposure
- Multiple organ dysfunction (MOD) vs non-MOD during index hospitalization
- MODn = 9,671
- non-MODn = 1,691,793reference
- Outcome
- Rehospitalizations, ED visits and health care costs
- Follow-up
- Up to 5 years after the index hospitalization
Methodological detailspropensity score weighted, nationwide insurance claims database
- Propensity score weighted
- Nationwide insurance claims database
Main finding
As reported in the abstract
- Propensity score weighted
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted IRR (95% CI) | |
|---|---|---|
| ED visits (infants) · 30 daysDifference persisted for years 1 through 5 | 1.76 (1.56–1.97) | |
| Rehospitalizations (infants) · 30 daysDifference persisted for years 1 through 5 | 12.45 (11.40–13.59) | |
| 0.050.21520Adjusted incidence rate ratio (log scale) |
| Outcome | MOD | non-MOD | P value |
|---|---|---|---|
| Annual health care costs (infants) · year 1 | mean $80 133 (SD $6543) | mean $5183 (SD $19) | P < 0.001 |
| Annual health care costs (children) · year 1 | mean $54 113 (SD $17 544) | mean $10 935 (SD $95) | P < 0.001 |
- Annual health care costs (infants): higher in all years through year 5
- Annual health care costs (children): higher in all years through year 5
ED visits (children)
- Similar pattern except at 30 days among those who acquired new organ-supportive technology during the index hospitalization
Rehospitalizations (children)
- Similar pattern observed among children
Original publication
Health Care Resource Use and Costs After Hospitalization With Multiple Organ Dysfunction in Children. JAMA Netw Open. Published 2 January 2025. doi:10. 1001/ jamanetworkopen. 2024. 56246
Composed by AI from the published abstract and checked against it. How Briefs are made →