Pediatric anesthesia & critical care

Health Care Resource Use and Costs After Hospitalization With Multiple Organ Dysfunction in Children

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

In this cohort study of nearly 1.7 million children, survivors of MOD accrued substantial ongoing health care resource use and cost burden after the index hospitalization.

Study context

Population
Infants (<1 year) and children (1–18 years) with an index hospitalization 2005–2018, US Optum Clinformatics claims databaseweighted sample
Participants
9,671 vs 1,691,793
Exposure
Multiple organ dysfunction (MOD) vs non-MOD during index hospitalization
  • MODn = 9,671
  • non-MODn = 1,691,793reference
Outcome
Rehospitalizations, ED visits and health care costs
Follow-up
Up to 5 years after the index hospitalization
Methodological detailspropensity score weighted, nationwide insurance claims database
  • Propensity score weighted
  • Nationwide insurance claims database

Main finding

As reported in the abstract

  • Propensity score weighted

Observational data: associations, not effects.

Further findings

OutcomeAdjusted IRR (95% CI)
ED visits (infants) · 30 daysDifference persisted for years 1 through 51.76 (1.56–1.97)
Rehospitalizations (infants) · 30 daysDifference persisted for years 1 through 512.45 (11.40–13.59)
OutcomeMODnon-MODP value
Annual health care costs (infants) · year 1mean $80 133 (SD $6543)mean $5183 (SD $19)P < 0.001
Annual health care costs (children) · year 1mean $54 113 (SD $17 544)mean $10 935 (SD $95)P < 0.001
  • Annual health care costs (infants): higher in all years through year 5
  • Annual health care costs (children): higher in all years through year 5

ED visits (children)

Similar pattern except at 30 days among those who acquired new organ-supportive technology during the index hospitalization

Rehospitalizations (children)

Similar pattern observed among children

Original publication

Health Care Resource Use and Costs After Hospitalization With Multiple Organ Dysfunction in Children. JAMA Netw Open. Published 2 January 2025. doi:10.1001/jamanetworkopen.2024.56246

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