Cardiac arrest & resuscitation
Heart rate and QRS duration as biomarkers predict the immediate outcome from pulseless electrical activity
Authors' conclusion
HR and QRSd convey information of the immediateoutcome during resuscitation from PEA.
Study context
- Population
- Patients with pulseless electrical activity (PEA) during in-hospital cardiac arrest at two US and one Norwegian hospital
- Participants
- 298 patients · 327 in-hospital cardiac arrest (IHCA) episodes
- Outcome
- Immediate outcome of PEA: transition to ROSC or no-ROSC (VF/VT, asystole or death), predicted by QRSd and HR
Methodological detailsmulticentre, joint longitudinal and competing risks model
- Multicentre
- Joint longitudinal and competing risks model
Main finding
As reported in the abstract
- Higher and rising HR: higher transition intensity to ROSC
- p < 0.001
- Lower and shrinking QRS duration (QRSd): increased transition intensity to ROSC
- p = 0.023
- Lower and shrinking QRSd: reduced transition intensity to no-ROSC
- p = 0.002
Observational data: associations, not effects.
Original publication
Heart rate and QRS duration as biomarkers predict the immediate outcome from pulseless electrical activity. Resuscitation. Published 16 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →