Heart rate recovery after orthostatic challenge and cardiopulmonary exercise testing in older individuals: prospective multicentre observational cohort study

BJA OpenPublished Prospective multicentre observational cohort study

Authors' conclusion

Prognostically significant heart rate recovery after exhaustive exercise is characterised by quantitative differences in heart rate recovery after orthostatic challenge.

Study context

Population
Older individuals scheduled for cardiopulmonary exercise testing (CPET) as part of routine carecompleted both tests
Participants
87 individuals
Exposure
HRR after orthostatic challenge vs HRR after maximal exercise
  • HRRexercise ≤12 beats min-1n = 27reference
  • HRRexercise >12 beats min-1n = 60
Outcome
Correlation between mean heart rate change every 10 s for 1 min after peak heart rate on standing and after exercise
Follow-up
1 min after peak heart rate

Main finding

As reported in the abstract

Correlation of mean heart rate change after standing and after exercise
Significantly correlated (R2)
0.81
P
P<0.0001

Observational data: associations, not effects.

Secondary outcomes

OutcomeMean difference (beats min-1) (95% CI)P value
HRRorthostatic by HRRexercise category3 (1–5)P < 0.0001

Peak VO2 with slower HRRorthostatic

Mean difference (ml kg-1 min-1) (95% CI)P value
Slower HRRorthostaticLower peak VO23.7 (0.7–6.8)P = 0.039

HRRorthostatic by HRRexercise category

HRRorthostatic unchanged in individuals with HRRexercise ≤12 beats min-1, lower when HRRexercise >12 beats min-1

Original publication

Heart rate recovery after orthostatic challenge and cardiopulmonary exercise testing in older individuals: prospective multicentre observational cohort study. BJA Open. Published 3 November 2023. doi:10.1016/j.bjao.2023.100238

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