Pediatric anesthesia & critical care

High-flow nasal oxygen versus standard care during flexible bronchoscopy in children under general anaesthesia—The BUFFALO randomised controlled pilot trial

Anaesth Crit Care Pain MedPublished Randomised controlled pilot trial

Authors' conclusion

The technique of using NHF during flexible bronchoscopies in children and the protocol for this trial were feasible in the two participating centres.

Study context

Population
Children aged >37 weeks gestational age to 16 years presenting for elective flexible bronchoscopy under GA89 eligible of 707 screened
Participants
81 children
Comparison
NHF vs Standard care
  • NHFn = 43
  • Standard caren = 38reference
Primary endpoint
Feasibility of recruitment to the protocol
Methodological detailsbi-centre, unmasked, parallel-group
  • Bi-centre
  • Unmasked
  • Parallel-group

Primary result

As reported in the abstract

Feasibility outcomes

Completion rate

100%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

High-flow nasal oxygen versus standard care during flexible bronchoscopy in children under general anaesthesia—The BUFFALO randomised controlled pilot trial. Anaesth Crit Care Pain Med. Published 11 July 2026. doi:10.1016/j.accpm.2026.101890

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