Pediatric anesthesia & critical care
Higher Survival With the Use of Extracorporeal Cardiopulmonary Resuscitation Compared With Conventional Cardiopulmonary Resuscitation in Children Following Cardiac Surgery: Results of an Analysis of the Get With The Guidelines-Resuscitation Registry*
Main finding · Survival to dischargeResult — go to the resultOR for survival to discharge 2.22 95% CI 1.7–2.9Authors' conclusion
E-CPR compared with C-CPR improved survival in children suffering cardiac arrest after cardiac surgery requiring CPR greater than or equal to 10 minutes.
Study context
- Population
- Cardiac surgical patients <18 years with in-hospital cardiac arrest receiving ≥10 min cardiopulmonary resuscitation (CPR), US Get With The Guidelines-Resuscitation registry, 2008–2020propensity-matched cohort analysed
- Participants
- 1,223 patients
- Exposure
- Extracorporeal CPR (E-CPR) vs conventional CPR (C-CPR)
- E-CPRn = 482
- C-CPRn = 741reference
- Outcome
- Survival to discharge
- Follow-up
- Discharge
Methodological detailspropensity-score matched, multicentre registry
- Propensity-score matched
- Multicentre registry
Main finding
As reported in the abstract
OR for survival to discharge
2.22
95% CI 1.7–2.9
P < 0.001
E-CPR vs C-CPR
OR for survival to discharge 2.22 (95% CI 1.7–2.9); P < 0.001
Observational data: associations, not effects.
Further findings
Duration of CPR · unmatched cohort
P < 0.001
| Outcome | OR for survival (95% CI) | P value | |
|---|---|---|---|
| Survival, centres contributing ≥1 E-CPR case (35 centres)353 E-CPR vs 353 C-CPR recipients · propensity matched analysis | 2.08 (1.6–2.8) | P < 0.001 | |
| 0.20.5125OR for survival (log scale) |
E-CPR utilization over the study period
- E-CPR utilization increased over the study period
- P < 0.001
Survival by CPR duration (subgroup)
- E-CPR survival only higher when CPR duration >18 min
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Higher Survival With the Use of Extracorporeal Cardiopulmonary Resuscitation Compared With Conventional Cardiopulmonary Resuscitation in Children Following Cardiac Surgery: Results of an Analysis of the Get With The Guidelines-Resuscitation Registry*. Crit Care Med. Published 8 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →