Perioperative medicine & outcomes

Home-based prehabilitation: a systematic review and meta-analysis of randomised trials

Br J AnaesthPublished Systematic review and meta-analysis of randomised trials

Pooled resultResult — go to the resultRelative risk 0.84 95% CI 0.72–0.98

Authors' conclusion

Home-based prehabilitation reduced the proportion of patients with postoperative complications, but with low certainty of evidence.

Study context

Population
Surgical patients
Participants
3,508 patients · 29 RCTs
Comparison
Home-based prehabilitation vs standard care
Outcome
Proportion of patients with postoperative complications
Methodological detailsRoB 2 risk of bias assessment
  • RoB 2 risk of bias assessment

Pooled result

As reported in the abstract

Relative risk

0.84

95% CI 0.72–0.98

P = 0.02

Events by group

Home-based prehabilitation vs Standard care
RR 0.84 (95% CI 0.72–0.98); P = 0.02

Further pooled results

OutcomeMD (m) (95% CI)P value
6-min walking testI2=4828.2 (9.5–46.9)P < 0.01
OutcomeMD (95% CI)P value
Preoperative depressionI2=0%−0.65 (−0.87 to −0.43)P < 0.001
Postoperative anxietyI2=0% · low certainty−0.50 (−0.75 to −0.25)P < 0.001
OutcomeMD (days) (95% CI)P value
Hospital LOSI2=45% · low certainty−0.32 (−0.61 to −0.03)P = 0.03
Adherence to home-based prehabilitation programs
82% · median

Original publication

Home-based prehabilitation: a systematic review and meta-analysis of randomised trials. Br J Anaesth. Published 6 February 2025. doi:10.1016/j.bja.2025.01.010

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