Perioperative medicine & outcomes
Home-based, virtually supported multimodal prehabilitation compared with usual care prior to major surgery: a multicentre, pragmatic pilot randomised trial
Authors' conclusion
A pragmatic, multicentre trial of virtually supported home-based multimodal prehabilitation is feasible.
Study context
- Population
- Adults ≥18 years preparing for planned inpatient non-cardiac, non-orthopaedic surgery, 5 Canadian centresof 154 eligible
- Participants
- 144 adults
- Comparison
- Virtually supported home-based multimodal prehabilitation vs usual care
- Primary endpoint
- Feasibility: recruitment (target >6 participants/centre/month), adherence (>75%), outcome completeness (>90%)
Methodological detailspragmatic, parallel-arm, multicentre, internal pilot, Recruitment 30 January to 11 July 2024, Mean participant age 62 (SD 12, range 28-85)
- Pragmatic
- Parallel-arm
- Multicentre
- Internal pilot
- Recruitment 30 January to 11 July 2024
- Mean participant age 62 (SD 12, range 28-85)
Primary result
As reported in the abstract
Feasibility
- Eligible participants randomised
- 93.5%
- Recruitment rate (participants/center/month), SD 4.4
- 8.4
- Trial-level median adherence (IQR 73-100)
- 95%
- Participants achieving >75% adherence
- 57 (78.5%)
- Patient-reported outcomes complete at 30 days
- 137 (95.1%)
- Patient-reported outcomes complete at 90 days
- 136 (94.4%)
- Patient-reported outcomes complete at 365 days
- 129 (89.5%)
Further findings
Barriers and facilitators (Theoretical Domains Framework (TDF) survey)
- TDF response profiles clustered in three groups
- 3
- Facilitators: beliefs about consequences and capabilities, intentions, social roles; barriers: environmental context and emotions
Association of TDF cluster membership with adherence
- Cluster membership strongly associated with adherence
- P < 0.001
- Variation in adherence explained by cluster membership
- 28%
Original publication
Home-based, virtually supported multimodal prehabilitation compared with usual care prior to major surgery: a multicentre, pragmatic pilot randomised trial. BJA Open. Published 16 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →