Hypoventilation in the post-anesthesia care unit (PACU) is associated with hypoventilation in the surgical ward: Post-hoc analysis of a randomized clinical trial
Authors' conclusion
In adults recovering from abdominal surgery, events of hypoventilation during the first postoperative hour are associated with similar events during the rest of the first 48 postoperative hours, with positive predictive value approaching 100%.
Study context
- Population
- Adults having abdominal surgery under GA, monitored with a respiratory volume monitor from PACU admission until 48 h after surgery or dischargeanalysed
- Participants
- 292 adults
- Comparison
- Low minute-ventilation (MV) event in last hour of PACU stay vs none
- Low MV event in PACUn = 20
- No low MV event in PACUn = 272reference
- Primary endpoint
- Low MV events lasting ≥2 min in the surgical ward
- Follow-up
- Rest of the first 48 postoperative hours
Methodological detailspost-hoc analysis, single-centre
- Post-hoc analysis
- Single-centre
Primary result
As reported in the abstract
Low MV event in PACU
20
events
No low MV event in PACU
22%
61 of 272
- Low MV events in the surgical ward, all patients
- 81 (28%)
Secondary outcomes
| Outcome | Low MV event in PACU | No low MV event in PACU |
|---|---|---|
| Incidence rate of low MV events per hour | 24 (95% CI 13–46) | 2 (95% CI 1–4) |
Original publication
Hypoventilation in the PACU is associated with hypoventilation in the surgical ward: Post-hoc analysis of a randomized clinical trial. J Clin Anesth. Published 10 November 2022. doi:10.
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