Perioperative medicine & outcomes
Immunometabolism, an emerging field in perioperative and critical care medicine: a narrative review
Main finding
As reported in the abstract
- Immunometabolism (metabolic adaptation of immune cells) largely underappreciated in the perioperative period, a strong translational model of dynamic metabolic shifts in acute inflammation
- Poor immunometabolic adaptation in chronic metabolic disease or acute injury can pathologically alter the inflammatory response, contributing to short- and long-term complications
- Interventions to modulate immunometabolism (immunonutrition in critical care) show heterogeneous results
- Potential perioperative interventions discussed: immunonutrition and mode of anaesthesia
Original publication
Immunometabolism, an emerging field in perioperative and critical care medicine: a narrative review. Br J Anaesth. Published 3 February 2026. doi:10. 1016/ j. bja. 2026. 01. 003
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