Impact of nitroglycerin‐induced vasodilation on stroke volume and diuretic response in acute heart failure: A protocol for a mechanistic trial

Acta Anaesthesiol ScandPublished Mechanistic study

Study context

Population
Patients hospitalised with acute HFplanned
Participants
21 patients
Planned comparison
Before vs after IV nitroglycerin
Methodological detailstrial protocol, prospective, single-centre, interventional, before-and-after, Continuous stroke volume estimates, total blood volume, vital signs and peripheral perfusion; cardiac, renal, volume and autonomic function assessed sequentially
  • Trial protocol
  • Prospective
  • Single-centre
  • Interventional
  • Before-and-after
  • Continuous stroke volume estimates, total blood volume, vital signs and peripheral perfusion; cardiac, renal, volume and autonomic function assessed sequentially

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Impact of nitroglycerin‐induced vasodilation on stroke volume and diuretic response in acute heart failure: A protocol for a mechanistic trial. Acta Anaesthesiol Scand. Published 5 February 2025. doi:10.1111/aas.14575

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