Cardiac arrest & resuscitation
Impact of number of defibrillation attempts on neurologically favourable survival rate in patients with Out-of-Hospital cardiac arrest
Authors' conclusion
Overall, a greater number of prehospital defibrillation attempts was associated with lower neurologically favourable survival at 1 month in patients with OHCA and shockable rhythm. However, an increasing number of shocks (up to the 4th shock) was associated with better neurological outcomes when considering only patients treated with adrenaline.
Study context
- Population
- Patients with witnessed out-of-hospital cardiac arrest (OHCA) and initial shockable rhythm, nationwide Japanese OHCA registry, 2006–2020of 1,802,084 OHCA
- Participants
- 81,056 patients
- Exposure
- Number of prehospital defibrillation attempts
- Outcome
- Neurologically favourable survival (cerebral performance category 1 or 2)
- Follow-up
- 1 month
Methodological detailsnationwide registry
- Nationwide registry
Main finding
As reported in the abstract
Neurologically favourable survival
Neurologically favourable survival (CPC 1 or 2)
18,080
22.3%
Observational data: associations, not effects.
Further findings
Favourable neurological survival by adrenaline (subgroup) · 1 month
- Without adrenaline: similar inverse trends
- With prehospital adrenaline: more defibrillation attempts associated with favourable neurological survival
Original publication
Impact of number of defibrillation attempts on neurologically favourable survival rate in patients with Out-of-Hospital cardiac arrest. Resuscitation. Published 22 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →