Impact of a Transitional Pain Service on postoperative opioid trajectories: a retrospective cohort study
Main finding · Monthly change in mean daily opioid doseResult — go to the resultDifference-in-difference −2.48 morphine milligram equivalents per month 95% CI −3.54 to −1.43Authors' conclusion
Patients enrolled in the Transitional Pain Service were able to achieve opioid dose reduction faster than in the control cohorts.
Study context
- Population
- Individuals who underwent surgery in Ontario, Canada, 2014 to 2018matched cohort pairs
- Participants
- 209 vs 209
- Exposure
- Transitional Pain Service vs no Transitional Pain Service
- Transitional Pain Servicen = 209
- Controlsn = 209reference
- Outcome
- Change in monthly mean daily opioid dosage (MME)
- Follow-up
- 12 months after surgery
Methodological detailsmatched cohort, administrative data, segmented regression
- Matched cohort
- Administrative data
- Segmented regression
Main finding
Monthly change in mean daily opioid dose
Difference-in-difference
−2.48 morphine milligram equivalents per month
95% CI −3.54 to −1.43
P = 0.003
Change by group
Transitional Pain Service
3.53
estimated decrease per month · 95% CI 2.67–4.39 · morphine milligram equivalents
Controls
1.05
estimated decline per month · 95% CI 0.43–1.66 · morphine milligram equivalents
Transitional Pain Service vs Controls
difference-in-difference −2.48 morphine milligram equivalents per month (95% CI −3.54 to −1.43); P = 0.003
As reported in the abstract
Observational data: associations, not effects.
Original publication
Impact of a Transitional Pain Service on postoperative opioid trajectories: a retrospective cohort study. Reg Anesth Pain Med. Published 8 November 2023. doi:10.
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