Cardiac arrest & resuscitation
Impact of coma duration on functional outcomes at discharge and long-term survival after cardiac arrest
Authors' conclusion
Shorter coma duration was associated with better functional outcome at discharge, but not with long-term survival.
Study context
- Population
- Post-cardiac arrest patients comatose on presentation who awakened during hospitalisation742 survived to discharge
- Participants
- 979 participants
- Exposure
- Short vs long coma duration
- Outcome
- Functional outcome (modified Rankin Scale) at hospital discharge and long-term survival
Main finding
As reported in the abstract
Discharge mRS ≤ 3 · Hospital discharge
- Shorter coma duration associated with higher proportion with discharge modified Rankin Scale (mRS) ≤ 3
- p < 0.001
- Median coma duration (days)
- 2 [IQR 1-4]
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Hazard of death per coma duration (Cox regression, adjusted) | 1.00 (0.97–1.03) | |
| 0.512Hazard ratio (log scale) |
| Outcome | P value |
|---|---|
| Long-term survival among survivors to dischargeNo difference; 3,136 person-years | P = 0.86 |
- Hazard of death per coma duration (Cox regression, adjusted): adjusted for age, location of arrest, Charlson Comorbidity Index, discharge mRS
Original publication
Impact of coma duration on functional outcomes at discharge and long-term survival after cardiac arrest. Resuscitation. Published 30 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →