Perioperative medicine & outcomes
Impact of emergence delirium on long-term survival in older patients after major noncardiac surgery: A longitudinal prospective observational study
Authors' conclusion
We did not find significant association between emergence delirium and worse long-term survival in older patients after general anesthesia and major surgery mainly for cancer.
Study context
- Population
- Patients aged 65–90 years admitted to post-anesthesia care unit (PACU) after major noncardiac surgery under GA, tertiary hospital in Beijing, China906 completed follow-up
- Participants
- 942 patients
- Exposure
- Emergence delirium vs no emergence delirium
- Emergence deliriumn = 331
- No emergence deliriumn = 575reference
- Outcome
- Overall survival
Methodological detailslongitudinal, single-centre, Followed up once a year for at least 3 years; Cox proportional hazard models
- Longitudinal
- Single-centre
- Followed up once a year for at least 3 years; Cox proportional hazard models
Main finding
As reported in the abstract
Deaths · median 43 months
Emergence delirium vs No emergence deliriumEstimate (95 % CI)P value
Unadjusted
HR 1.10(0.81–1.48)
P = 0.547Adjusted
aHR 0.96(0.70–1.32)
P = 0.797Observational data: associations, not effects.
Secondary outcomes
%
| Outcome | Emergence delirium | No emergence delirium | Estimate | P value | |
|---|---|---|---|---|---|
| Recurrence-free survival (events) · end of follow-up (median 43 months)Cox proportional hazard models | 22 | 21 | unadjusted HR for recurrence or death 1.08 (95 % CI 0.81–1.45) | P = 0.598 | |
| Recurrence-free survival (events) · end of follow-up (median 43 months)Cox proportional hazard models | adjusted HR for recurrence or death 0.94 (95 % CI 0.69–1.28) | P = 0.695 | |||
| Event-free survival (events) · end of follow-up (median 43 months)Cox proportional hazard models | 48 | 47 | unadjusted HR for an event 1.06 (95 % CI 0.87–1.29) | P = 0.563 | |
| Event-free survival (events) · end of follow-up (median 43 months)Cox proportional hazard models | adjusted HR for an event 0.98 (95 % CI 0.80–1.21) | P = 0.875 | |||
| 0.512Ratio (log scale) |
Original publication
Impact of emergence delirium on long-term survival in older patients after major noncardiac surgery: A longitudinal prospective observational study. J Clin Anesth. Published 22 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →