Impact of erythromycin and metoclopramide on gastric emptying of solids in term pregnant women scheduled for elective cesarean delivery: A randomized controlled trial
Authors' conclusion
Premedication with oral erythromycin or metoclopramide before elective cesarean delivery accelerated gastric emptying and may reduce aspiration risk after a standard meal.
Study context
- Population
- Non-laboring term pregnant women scheduled for elective cesarean delivery
- Participants
- 150 women
- Comparison
- Oral erythromycin 400 mg or metoclopramide 10 mg vs placebo after a standard meal
- Primary endpoint
- Mean gastric volume (ultrasonography)
- Follow-up
- After six hours of fasting
Methodological detailsdouble-blinded, placebo-controlled
- Double-blinded
- Placebo-controlled
Primary result
As reported in the abstract
Gastric volume · 6 h
P < 0.001
Secondary outcomes
Low-risk gastric contents · 6 h after standard meal
P = 0.017
Gastric emptying fraction · 5th and 6th h
- Significantly higher in E and M vs C
Half-time gastric emptying and gastric emptying time
- Shortest in E and M
Original publication
Impact of erythromycin and metoclopramide on gastric emptying of solids in term pregnant women scheduled for elective cesarean delivery: A randomized controlled trial. Anaesth Crit Care Pain Med. Published 14 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →