Hemodynamics, fluids & transfusion
Impact of missing values on the ability of the acute physiology and chronic health evaluation III and Japan risk of death models to predict mortality
Authors' conclusion
An increased number of missing physiological variables resulted in falsely low predicted mortality rates and high SMRs.
Study context
- Population
- ICU patients in the Japanese Intensive care PAtient Database (JIPAD), April 2015–March 2019
- Participants
- 61,357 patients · 57 ICUs
- Exposure
- Acute Physiology and Chronic Health Evaluation (APACHE) III vs Japan Risk of Death (JROD)
- Outcome
- SMR (observed vs predicted mortality) by number and category of missing variables
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
SMR by number of missing values
- APACHE III and JROD standardized mortality ratio (SMRs) increased as the number of missing values increased
- APACHE III SMR elevated in facilities with a larger proportion missing in each APS category, arterial blood gas, albumin, glucose and bilirubin
- Facilities with a high proportion of missing albumin data preserved their SMRs in only the JROD model
Observational data: associations, not effects.
Original publication
Impact of missing values on the ability of the acute physiology and chronic health evaluation III and Japan risk of death models to predict mortality. J Crit Care. Published 22 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →