Perioperative medicine & outcomes
Impact of peri‐operative frailty and operative stress on post‐discharge mortality, readmission and days at home in Medicare beneficiaries
Study context
- Population
- Medicare fee-for-service beneficiaries aged ≥ 65 years undergoing non-cardiac surgery listed in Operative Stress Score categories, 2015–201916.8% frail
- Participants
- 1,019,938 beneficiaries
- Exposure
- Claims-based frailty index categories (pre-frail, mildly frail, moderate-to-severely frail vs robust) across Operative Stress Score categories 1–5
- Outcome
- All-cause mortality
- Follow-up
- 30 days and 365 days after surgery
Methodological detailsMedicare claims data, 7.125% random sample
- Medicare claims data
- 7.125% random sample
Main finding
As reported in the abstract
All-cause mortality, moderate-to-severe frailty vs robust, within each Operative Stress Score category
Hazard ratio
1.59-3.91
30 days; range across Operative Stress Score categories
Hazard ratio
1.30-4.04
365 days; range across Operative Stress Score categories
Observational data: associations, not effects.
Further findings
Cumulative incidence of mortality by Operative Stress Score category · 365 days
- Generally increased with Operative Stress Score category; lowest (Operative Stress Score 2)
- 5.0%
- Highest (Operative Stress Score 4)
- 24.9%
Postoperative outcomes: variation by frailty vs operative stress
- Variation by frailty level much greater than variation by operative stress category
Original publication
Impact of peri‐operative frailty and operative stress on post‐discharge mortality, readmission and days at home in Medicare beneficiaries. Anaesthesia. Published 22 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →