Perioperative medicine & outcomes

Surgical time, peri-operative major adverse cardiac and cerebral events and hospital stay in noncardiac surgery: insights from 7-day service implementation: A retrospective case-control study

Eur J AnaesthesiolPublished Nested case-control study

Authors' conclusion

Night-shift surgery was an independent risk factor for peri-operative MACCE in noncardiac surgery patients. The 7-day service policy reduced night-shift procedures and increased those at weekends, without increasing the risk of MACCE. It was also associated with shorter hospital stays.

Study context

Population
Patients undergoing noncardiac surgery, single-centre university hospital, January 2018 to December 2021
Participants
2,543 vs 10,683
Comparison
Night-shift or weekend surgery vs daytime/weekday surgery; prepolicy vs postpolicy 7-day service
  • Casesn = 2,543
  • Controlsn = 10,683reference
Outcome
Peri-operative MACCE
Methodological detailssingle-centre, retrospective
  • Single-centre
  • Retrospective

Main finding

As reported in the abstract

Peri-operative MACCE, night-shift vs other surgery
Estimate (95% CI)P value
Night shiftmultivariable logistic regression
fully adjusted OR 1.54(1.3–1.8)
P < 0.001
Weekendafter full adjustment
OR 1.15(0.96–1.38)
P = 0.13
Incidence of MACCE, night-shift vs other procedures
28.7 vs. 18.2%, P < 0.001

Observational data: associations, not effects.

Further findings

MACCE, sensitivity model including both night-shift and weekend surgery

OR (95% CI)P value
Night shift1.54 (1.3–1.82)P < 0.001
Weekend1.17 (0.97–1.4)P = 0.09
OutcomeSMD
Night-shift and weekend procedures, prepolicy vs postpolicy 7-day servicePrepolicy vs Postpolicy · night-shift procedures 16.1% vs. 3.7%0.42
Night-shift and weekend procedures, prepolicy vs postpolicy 7-day servicePrepolicy vs Postpolicy · weekend procedures 5.5 vs. 13.3%0.27

Hospital LOS, night-shift vs other procedures

Longer hospital stays with night-shift procedures
172 vs. 155 h, P < 0.01

Costs, night-shift vs other procedures

Higher costs with night-shift procedures
48 529 vs. 37 962 yuan, P < 0.001

Postpolicy period, weekend surgery: hospital LOS and MACCE

Shorter hospital stay with weekend surgery
139 vs. 160 h, P < 0.001
No increase in MACCE with weekend surgery
18.7 vs. 19.4%, P = 0.53

Original publication

Surgical time, peri-operative major adverse cardiac and cerebral events and hospital stay in noncardiac surgery: insights from 7-day service implementation: A retrospective case-control study. Eur J Anaesthesiol. Published 6 August 2026. doi:10.1097/eja.0000000000002474

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