Neuroanesthesia & neurocritical care
Impact of rehabilitation in the neurointensive care unit on long‐term survival in patients with traumatic brain injury
Main finding · MortalityResult — go to the resultAdjusted hazard ratio 0.56 95% CI 0.36–0.89Authors' conclusion
Patients receiving EIR had better long-term survival, with both groups experiencing the highest mortality rate early on.
Study context
- Population
- Adults aged 18–67 years with moderate to severe traumatic brain injury (TBI) (GCS 3–14) admitted to the Neurointensive Care Unit (NICU) for >72 h, 2010–2022
- Participants
- 698 adults
- Exposure
- Early interdisciplinary rehabilitation (EIR) vs Standard of care (SC)
- EIRn = 461
- SCn = 237reference
- Outcome
- Long-term mortality (from start of follow-up until end of follow-up)
Methodological detailsinverse probability of treatment weighted
- Inverse probability of treatment weighted
Main finding
Mortality · end of follow-up
Adjusted hazard ratio
0.56
95% CI 0.36–0.89
P = 0.015
Events by group
EIR vs SC
adjusted HR 0.56 (95% CI 0.36–0.89); P = 0.015
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted HR (95% CI) | P value | |
|---|---|---|---|
| Mortality at 30 days | 0.57 (0.37–0.87) | P = 0.010 | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Mortality at 30 days
- Both groups had the highest mortality rate within 30 days
Original publication
Impact of rehabilitation in the neurointensive care unit on long‐term survival in patients with traumatic brain injury. Acta Anaesthesiol Scand. Published 18 March 2025. doi:10.
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