Neuroanesthesia & neurocritical care
Assessing the impact of early progressive mobilization on moderate-to-severe traumatic brain injury: a randomized controlled trial
Authors' conclusion
The early progressive out-of-bed mobilization protocol can enhance mobility and functional outcomes and shorten ICU stay and ventilation duration of patients with moderate-to-severe TBI.
Study context
- Population
- Intensive care unit (ICU)-admitted patients with moderate to severe traumatic brain injury (TBI), trauma ICU of a medical center
- Participants
- 65 patients
- Comparison
- Early progressive mobilization (EPM) vs early progressive upright positioning (EPUP)
- EPMn = 33
- EPUPn = 32reference
- Primary endpoint
- Perme ICU Mobility Score
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
- EPM significantly outperformed EPUP in Perme ICU Mobility Score
Secondary outcomes
| Outcome | Difference (days) | P value |
|---|---|---|
| ICU LOSShorter ICU stay with EPM | 5.9 | P < 0.001 |
| Duration of ventilationShorter ventilation duration with EPM | 6.7 | P = 0.001 |
FIM-motor score
- EPM significantly outperformed EPUP in FIM-motor score
Phase angle (PhA)
- No significant differences in PhAs
Original publication
Assessing the impact of early progressive mobilization on moderate-to-severe traumatic brain injury: a randomized controlled trial. Crit Care. Published 22 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →