Inadequate spinal anesthesia for postpartum tubal ligation: a single-center retrospective analysis (2003–2025)
Main finding · Inadequate blockResult — go to the resultOdds ratio 0.48 95% CI 0.26–0.86Authors' conclusion
Intrathecal hyperbaric bupivacaine at a dose ≥13.5 mg was associated with lower odds of inadequate anesthesia for postpartum tubal ligation compared with 10.5-12 mg in the context of an evolving institutional practice.
Study context
- Population
- Patients undergoing postpartum tubal ligation with spinal anesthesia with hyperbaric bupivacaine, 2003–2025
- Participants
- 594 patients
- Exposure
- Intrathecal hyperbaric bupivacaine high vs middle vs low dose
- Low dosen = 14
- Middle dosen = 336reference
- High dosen = 244
- Outcome
- Inadequate block (supplementation with IV analgesics, or failed block with repeat neuraxial anesthesia or conversion to GA)
Methodological detailssingle-centre
- Single-centre
Main finding
Inadequate block
Odds ratio
0.48
95% CI 0.26–0.86
P = 0.015
Events by group
High dose vs Middle dose
OR 0.48 (95% CI 0.26–0.86); P = 0.015
As reported in the abstract
- Inadequate block overall
- 132/594 (22.2%)
Observational data: associations, not effects.
Further findings
Factors associated with inadequate block
| OR (CI) | P value | ||
|---|---|---|---|
| More recent years since start of study | 0.95 (0.9–1) | P = 0.029 | |
| Longer surgical duration | 1.03 (1.01–1.04) | P < 0.001 | |
| Higher intrathecal fentanyl dose | 1.03 (1–1.05) | P = 0.043 | |
| 0.512Odds ratio (log scale) |
Original publication
Inadequate spinal anesthesia for postpartum tubal ligation: a single-center retrospective analysis (2003–2025). Int J Obstet Anesth. Published 25 June 2026. doi:10. 1016/ j. ijoa. 2026. 105227
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