Obstetric anesthesia

Incidence of Interstitial Alveolar Syndrome on Point-of-Care Lung Ultrasonography in Pre-eclamptic Women With Severe Features: A Prospective Observational Study

Anesth AnalgPublished Prospective observational study

Authors' conclusion

We conclude that ultrasonographic pulmonary interstitial syndrome is present in more than half of the women with pre-eclampsia with severe features and correlates with diastolic dysfunction, high blood pressure records, and acute-onset breathlessness.

Study context

Population
Parturients with pre-eclampsia with severe features
Participants
70 participants
Outcome
Incidence of interstitial alveolar syndrome (B-lines) on lung ultrasonography (LUS)
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

B-lines on LUS

B-lines at admission (45/70 vs 25/70 without B-lines; P = .02)

64.3%

B-lines before delivery (46/70 vs 24/70 without B-lines; P = .01)

65.7%

B-lines 24 hours postpartum (41/70 versus 29/70 without B-lines; P = .15)

58.6%

Observational data: associations, not effects.

Further findings

Low to moderate pulmonary fluid burden at admission

Nearly all patients with low to moderate severity
94.3%

Diastolic dysfunction on echocardiography

Diastolic dysfunction (n = 33/70)
47.1%
B-lines among those with diastolic dysfunction
32/33
Correlation of total B-line score with E/e' ratio in diastolic dysfunction (P < .001)
r = 0.848

B-lines in symptomatic women on admission

Breathlessness with B-lines (11/11)
100%
Facial puffiness with B-lines (16/16)
100%

Original publication

Incidence of Interstitial Alveolar Syndrome on Point-of-Care Lung Ultrasonography in Pre-eclamptic Women With Severe Features: A Prospective Observational Study. Anesth Analg. Published 20 January 2023. doi:10.1213/ane.0000000000006367

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