Cardiac arrest & resuscitation

Incidence of Out-of-Hospital Cardiac Arrest on a Postholiday Weekday

JAMA Netw OpenPublished Nationwide cohort study

An erratum to this article was published (JAMA Netw Open, 1 Apr 2026 ↗)

Main finding · Daily OHCA incidenceResult — go to the resultIncidence rate ratio 1.09 95% CI 1.08–1.11

Authors' conclusion

In this nationwide cohort study, a postholiday weekday was associated with a significantly elevated out-of-hospital cardiac arrest incidence in South Korea, particularly after consecutive rest days and among vulnerable populations.

Study context

Population
Adult OHCA cases occurring on weekdays (excluding holidays), South Korea, 2013–2023
Participants
203,471 OHCA cases
Exposure
Postholiday weekday vs baseline weekdays
  • Postholiday weekdayn = 49,199
  • Baseline weekdaysn = 154,272reference
Outcome
OHCA IRR, postholiday weekday vs baseline weekdays
Methodological detailsregistry-based (OHCA Surveillance database), negative binomial regression
  • Registry-based (OHCA Surveillance database)
  • Negative binomial regression

Main finding

Daily OHCA incidence

Incidence rate ratio

1.09

95% CI 1.08–1.11

P < 0.001

By group

Postholiday weekday vs Baseline weekdays
IRR 1.09 (95% CI 1.08–1.11); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeIRR (95% CI)P value
Subgroup: age >65 y1.03 (1.02–1.04)P < 0.001
Subgroup: cardiac cause1.02 (1.01–1.04)P < 0.001
Subgroup: nonshockable rhythms1.03 (1.01–1.04)P < 0.001
Duration of preceding holiday (dose-response)After single-day holidays vs Baseline weekdays1.03 (0.98–1.08)P = 0.25
Duration of preceding holiday (dose-response)After 2-day holidays vs Baseline weekdays1.10 (1.08–1.11)P < 0.001
Duration of preceding holiday (dose-response)After 3-day holidays vs Baseline weekdays1.09 (1.03–1.15)P = 0.003
Duration of preceding holiday (dose-response)After holidays ≥4 days vs Baseline weekdays1.10 (1.03–1.18)P = 0.008
Type of preceding holidayWeekend vs Baseline weekdays1.09 (1.07–1.11)P < 0.001
Type of preceding holidayMixed vs Baseline weekdays1.10 (1.06–1.14)P < 0.001
Type of preceding holidayPublic vs Baseline weekdays1.03 (0.97–1.09)P = 0.24
Type of preceding holidayTemporary vs Baseline weekdays1.01 (0.89–1.13)P = 0.86

Duration of preceding holiday (dose-response)

A clear dose-response association was observed

Original publication

Incidence of Out-of-Hospital Cardiac Arrest on a Postholiday Weekday. JAMA Netw Open. Published 2 March 2026. doi:10.1001/jamanetworkopen.2026.0832

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