Perioperative medicine & outcomes
Individual FiO2 guided by SPO2 prevents hyperoxia and reduces postoperative atelectasis in colorectal surgery: A randomized controlled trial
Authors' conclusion
The use of iFiO2 during operation significantly reduces the LUS and pulmonary atelectasis in patients undergoing laparoscopic colorectal surgery under general anesthesia.
Study context
- Population
- Inpatients undergoing elective laparoscopic colorectal surgery, single tertiary care hospital in China, August 2021–May 2022
- Participants
- 84 inpatients
- Comparison
- Individualised FiO2 based on physiological SpO2 vs fixed 60% FiO2
- Primary endpoint
- Lung ultrasound score (LUS)
- Follow-up
- 30 min after extubation
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
LUS
Individualized fraction of inspired oxygen (iFiO2)
5
as printed [ , ] 4–7
fFiO2
8
as printed [ , ] 4–10
P = 0.03
Secondary outcomes
Significant atelectasis (LUS criterion)
P = 0.025
PaO2, A-aDO2 and Qs/Qt · End of surgery
- Significantly reduced in iFiO2 vs fFiO2
Original publication
Individual FiO2 guided by SPO2 prevents hyperoxia and reduces postoperative atelectasis in colorectal surgery: A randomized controlled trial. J Clin Anesth. Published 26 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →