Perioperative medicine & outcomes

Individualised positive end-expiratory pressure to minimise driving pressure and postoperative pulmonary complications in minimally invasive thoracic and abdominal surgery a systematic review and meta-analysis

Br J AnaesthPublished Systematic review and meta-analysis

Pooled resultResult — go to the resultRelative risk 0.67 95% CI 0.56–0.79

Authors' conclusion

Individualised PEEP was associated with fewer postoperative pulmonary complications and lower driving pressures during minimally invasive surgery

Study context

Population
Patients undergoing minimally invasive thoracic and abdominal surgery
Participants
3,295 patients · 30 studies
Comparison
Individualised PEEP vs lung-protective ventilation
Outcome
Postoperative pulmonary complication
Methodological detailsrandom-effects models, prespecified subgroup analyses by surgery type, post hoc subgroup analyses
  • Random-effects models
  • Prespecified subgroup analyses by surgery type
  • Post hoc subgroup analyses

Pooled result

As reported in the abstract

Relative risk

0.67

95% CI 0.56–0.79

Individualised PEEP vs Lung-protective ventilation
RR 0.67 (95% CI 0.56–0.79)

Further pooled results

OutcomeMean difference (95% CI)
Driving pressureI2=86.6%−3.17 (−3.84 to −2.50)

Original publication

Individualised positive end-expiratory pressure to minimise driving pressure and postoperative pulmonary complications in minimally invasive thoracic and abdominal surgery a systematic review and meta-analysis. Br J Anaesth. Published 10 April 2026. doi:10.1016/j.bja.2026.02.036

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