Respiratory failure & ventilation
Individualized positive end-expiratory pressure (PEEP) guided by electrical impedance tomography (EIT) in patients undergoing general anesthesia: A systematic review and meta-analysis
Authors' conclusion
Our meta-analysis suggests potential benefits of EIT-guided individualized PEEP setting in improving intraoperative oxygenation and lung compliance in patients undergoing general anesthesia.
Study context
- Population
- Patients undergoing GA
- Participants
- 272 patients · 5 studies
- Comparison
- EIT-guided PEEP vs Fixed PEEP or other titration
- Outcome
- Oxygenation index (OI), lung compliance and number of postoperative pulmonary complications (PPCs)
Methodological detailssensitivity analysis
- Sensitivity analysis
Pooled result
As reported in the abstract
EIT-guided PEEP vs Fixed PEEP or other titrationOdds ratio (95% CI)P value
Intraoperative OI
95.73(49.10–142.37)
P < 0.0001Lung compliance
7.69(5.55–9.83)
P < 0.00001Postoperative PPCs
0.87(0.41–1.82)
P = 0.71Further pooled results
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Number of IV vasoactive drugs | 1.22 (0.68–2.21) | P = 0.51 | |
| 0.512Odds ratio (log scale) |
| Outcome | OR (95% CI) | P value |
|---|---|---|
| Intraoperative MAP | 2.07 (−1.00 to 5.13) | P = 0.19 |
Original publication
Individualized PEEP guided by EIT in patients undergoing general anesthesia: A systematic review and meta-analysis. J Clin Anesth. Published 25 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →