Respiratory failure & ventilation

Inferior vena cava distensibility during pressure support ventilation: a prospective study evaluating interchangeability of subcostal and trans‑hepatic views, with both M‑mode and automatic border tracing

J Clin Monit ComputPublished Prospective observational study

Authors' conclusion

In PSV ventilated patients, we found that IVC-DI calculated with M-mode is not interchangeable with ABT measurements. Moreover, the IVC-DI gathered from SC or TH view produces not comparable results, mainly in terms of precision.

Study context

Population
Intensive Care Unit (ICU) patients ventilated in pressure support ventilation (PSV)
Exposure
Inferior Vena Cava (IVC) distensibility by M-mode vs automated border tracking (ABT), and subcostal vs trans-hepatic view
Outcome
Interchangeability of IVC and distensibility index (DI) measurements by M-mode and ABT across SC and TH views (Bland-Altman mean bias, LoA; Spearman correlation)
Methodological details2 × 2 factorial design
  • 2 × 2 factorial design

Main finding

As reported in the abstract

IVC-DI agreement
ABT vs M-mode · limits of agreement (LoA) −18.4% to 30.2%, ICC = 0.52
mean bias (SC view) 5.9%
ABT vs M-mode · LoA −8.0% to 20.4%, ICC = 0.67
mean bias (trans-hepatic (TH) view) 6.2%
TH vs SC · LoA −13.7% to 17.5%
mean bias (M-mode) 1.9%
TH vs SC · LoA −19.6% to 21.9%
mean bias (ABT) 1.1%
Correlation generally suboptimal
r = 0.43 to 0.60

Observational data: associations, not effects.

Further findings

IVC visualization success — SC
100%
IVC visualization success — TH view unattainable
17.4%

Original publication

Inferior vena cava distensibility during pressure support ventilation: a prospective study evaluating interchangeability of subcostal and trans‑hepatic views, with both M‑mode and automatic border tracing. J Clin Monit Comput. Published 31 May 2024. doi:10.1007/s10877-024-01177-8

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