Perioperative medicine & outcomes
Influence of the type of anaesthesia on acute kidney injury after nephrectomy: a randomised controlled trial
Primary resultResult — go to the resultAbsolute risk difference 4.6 % 95% CI −4.9-14.0%Authors' conclusion
The type of anaesthetic maintenance drug (propofol vs. desflurane) did not affect the incidence of acute kidney injury after nephrectomy.
Study context
- Population
- Adults with renal cell carcinoma undergoing nephrectomy317 analysed
- Participants
- 43 vs 36
- Comparison
- Propofol TCI vs desflurane maintenance anaesthesia
- Propofoln = 43
- Desfluranen = 36reference
- Primary endpoint
- Incidence of AKI (serum creatinine component of KDIGO criteria)
- Follow-up
- Within 7 postoperative days
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Absolute risk difference
4.6 %
95% CI −4.9-14.0%
P = 0.347
Events by treatment group
Propofol vs Desflurane
absolute risk difference 4.6 % (95% CI −4.9-14.0%); P = 0.347
Further findings
AKI overall and severity
- Postoperative AKI, all patients
- 79 (25%)
- Stage 1
- 76
- Stage 3
- 1
- Stage 2
Original publication
Influence of the type of anaesthesia on acute kidney injury after nephrectomy: a randomised controlled trial. Anaesthesia. Published 26 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →