Perioperative medicine & outcomes
Influence of different anesthetic depth on postoperative delirium in elderly pre-frail patients undergoing abdominal surgery
Authors' conclusion
The elderly pre-frail patients under light anesthesia (with high CSI score) may have lower incidence of postoperative delirium and better outcome.
Study context
- Population
- Elderly pre-frail patients (>65 years, Modified Frailty Index (mFI-5) score 1–2) scheduled for selective abdominal surgery under GA
- Participants
- 150 patients
- Comparison
- Light vs deep anesthesia
- Primary endpoint
- Incidence of postoperative delirium
- Follow-up
- Within 3 days postoperatively
Primary result
As reported in the abstract
Postoperative delirium
- Light anesthesia (LA) vs deep anesthesia (DA): P < 0.05
Further findings
| Outcome | P value |
|---|---|
| QoR-15 scores · first postoperative daySignificantly higher in LA | P < 0.05 |
| VAS scores · 2 days following surgerySignificantly higher in DA | P < 0.05 |
Original publication
Influence of different anesthetic depth on postoperative delirium in elderly pre-frail patients undergoing abdominal surgery. Perioper Med (Lond). Published 28 July 2025. doi:10.
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