Cardiothoracic & vascular anesthesia
Preoperative Modified Frailty Index-11 versus EuroSCORE II in Predicting Postoperative Mortality and Complications in Elderly Patients Who Underwent Elective Open Cardiac Surgery: A Retrospective Cohort Study
Authors' conclusion
The mFI-11 and EuroSCORE II demonstrated good discrimination in ROC analysis, with EuroSCORE II showing superior predictive accuracy for in-hospital mortality in elderly elective cardiac surgery patients.
Study context
- Population
- Elderly patients age ≥60 years undergoing elective open-heart surgery on pump, tertiary centre in southern Thailand, January 2017–December 2022
- Exposure
- mFI-11 vs EuroSCORE II vs Combined
- Outcome
- In-hospital mortality (discrimination, AUC)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
In-hospital mortality, AUC
mFI-11
0.733
AUC · 95% CI 0.6157–0.8499
EuroSCORE II
0.793
AUC · 95% CI 0.6826–0.9026
Combined
0.78
AUC · 95% CI 0.6686–0.893
- Actual in-hospital mortality, all patients
- 2.5%
Observational data: associations, not effects.
Further findings
| Outcome | mFI-11 | EuroSCORE II |
|---|---|---|
| Postoperative complications, AUC (cardiac, respiratory, neurologic, renal) | ||
| Cardiac | 0.558 (95% CI, 0.5101-0.6063) | 0.553 (95% CI, 0.5038-0.6013) |
| Respiratory | 0.606 (95% CI, 0.5542-0.6581) | 0.631 (95% CI, 0.578-0.6836) |
| Neurologic | 0.543 (95% CI, 0.4533-0.6337) | 0.619 (95% CI, 0.5306-0.7076) |
| Renal | 0.652 (95% CI, 0.5859-0.7179) | 0.702 (95% CI, 0.6378-0.7657) |
Multiple logistic regression for mortality
- Neither score independently predicted mortality; combining did not significantly enhance predictive power
Original publication
Preoperative Modified Frailty Index-11 versus EuroSCORE II in Predicting Postoperative Mortality and Complications in Elderly Patients Who Underwent Elective Open Cardiac Surgery: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 17 August 2024. doi:10. 1053/ j. jvca. 2024. 08. 018
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