Pediatric anesthesia & critical care

Inhalation anesthesia without any intravenous management for pediatric proton beam therapy

Paediatr AnaesthPublished Retrospective descriptive study with literature review

Authors' conclusion

Inhalation anesthesia without any intravenous management for pediatric proton therapy is, in our experience, an effective technique with a complication rate similar to other anesthetic approaches.

Study context

Population
Children undergoing proton beam therapy under anesthesia, June 2020–August 2021873 sessions
Participants
31 children
Outcome
Anesthesia induction time and anesthesia recovery time
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Mean anesthesia induction time

SD = 0.7 4.1 min (95% CI [3.9, 4.4])

Mean anesthesia recovery time

SD = 4.1 13.8 min (95% CI [12.3, 15.3])

Observational data: associations, not effects.

Further findings

Published studies on anesthesia for pediatric proton therapy (literature review)

Papers addressing anesthetic management, of 1082 found, all using intravenous or combined intravenous and inhalation anesthesia
11

Safety

Non-serious adverse effects

Percentage of non-serious adverse effects
0.7% (Clopper-Pearson 95% CI [0.3, 1.5])

Serious adverse effects

Percentage of serious adverse effects
0.1% (Clopper-Pearson 95% CI [0, 0.6])
No statistically significant difference vs other published works with different anesthetic approaches

Original publication

Inhalation anesthesia without any intravenous management for pediatric proton beam therapy. Paediatr Anaesth. Published 1 August 2023. doi:10.1111/pan.14739

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