Perioperative medicine & outcomes
Insignificant influence of the intertransverse process block for major breast cancer surgery: a randomized, blinded, placebo-controlled, clinical trial
Authors' conclusion
Following major reconstructive breast cancer surgery, a preoperative multiple-injection ITP block neither reduces 24-hour opioid consumption postoperatively nor promotes substantial clinical positive outcomes.
Study context
- Population
- Patients with breast cancer scheduled for unilateral subpectoral implant-based primary breast reconstruction involving mastectomy with complete fascial dissection of the major pectoral muscle58 screened
- Participants
- 36 patients
- Comparison
- Multiple-injection intertransverse process (ITP) block vs placebo ITP block
- Primary endpoint
- Total opioid consumption
- Follow-up
- First 24 postoperative hours
Methodological detailsblinded, placebo-controlled, prospective
- Blinded
- Placebo-controlled
- Prospective
Primary result
As reported in the abstract
Opioid consumption
P = 0.5
Secondary outcomes
Secondary outcomes (opioid consumption at 4-h intervals, pain, satisfaction, time to first opioid, ambulation, discharge, opioid-related side effects, quality of recovery)
- No consequential clinically relevant results
Original publication
Insignificant influence of the intertransverse process block for major breast cancer surgery: a randomized, blinded, placebo-controlled, clinical trial. Reg Anesth Pain Med. Published 11 May 2023. doi:10.
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