Pediatric anesthesia & critical care
International multi-institutional external validation of preoperative risk scores for 30-day in-hospital mortality in paediatric patients
Authors' conclusion
The intrinsic surgical risk score performed better than the PRAm, but both resulted in large numbers of false positives.
Study context
- Population
- Paediatric surgical patients, 56 US and Dutch hospitals (Multicenter Perioperative Outcomes Group (MPOG) registry)
- Participants
- 606,488 patients · 56 hospitals
- Comparison
- Pediatric Risk Assessment (PRAm) score vs intrinsic surgical risk score
- Outcome
- 30-day in-hospital mortality
- Follow-up
- 30 days
Methodological detailsmulticentre registry, international
- Multicentre registry
- International
Performance
As reported in the abstract
Discrimination for 30-day mortality (external validation)
| Test or model | AUROC | AUC-PR |
|---|---|---|
| PRAm | 0.856 (95% CI 0.844-0.869) | 0.008 |
| Intrinsic surgical risk score | 0.925 (0.914-0.936) | 0.085 |
AUROC
PRAm0.856 (95% CI 0.844-0.869)
Intrinsic surgical risk score0.925 (0.914-0.936)
AUC-PR
PRAm0.008
Intrinsic surgical risk score0.085
- 30-day mortality
- 0.14% (822/606 488)
Secondary outcomes
Calibration and decision curve analysis, both scores
- Calibration favourable for both scores because of the large cluster of low-probability cases
- Decision curve analyses showed limited benefit to using either score
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
International multi-institutional external validation of preoperative risk scores for 30-day in-hospital mortality in paediatric patients. Br J Anaesth. Published 29 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →