Pediatric anesthesia & critical care

Performance of published scoring tools for predicting the risk of perioperative respiratory adverse events in children – An evaluation in a large paediatric cohort

Anaesth Crit Care Pain MedPublished Post-hoc secondary analysis

Authors' conclusion

The discriminative ability of existing PRAE risk prediction tools was poor in our test group.

Study context

Population
Children undergoing GAcases of GA
Participants
12,364 children
Comparison
Six published perioperative respiratory adverse events (PRAE) risk prediction scores
Primary endpoint
AUC as the primary measure of predictive performance of each risk prediction score
Methodological detailsexternal validation of risk prediction scores
  • External validation of risk prediction scores

Primary result

As reported in the abstract

AUC for prediction of PRAE
GroupAUC (any PRAE)
OLDS score0.649

OLDS score

AUC (any PRAE)0.649
AUC range across six tools, any PRAE
0.562-0.649
AUC range across six tools, severe PRAE
0.509-0.614

Further findings

PRAE rate

Any PRAE
11.9%
Severe PRAE (bronchospasm and/or laryngospasm)
2.0%

Original publication

Performance of published scoring tools for predicting the risk of perioperative respiratory adverse events in children – An evaluation in a large paediatric cohort. Anaesth Crit Care Pain Med. Published 17 February 2026. doi:10.1016/j.accpm.2026.101776

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