Paediatric anaesthesia & critical care
Association between supraglottic airway device use and respiratory adverse events during airway management in children with airway hyperresponsiveness: a report from the Japan Paediatric Difficult Airway in Anaesthesia (J-PEDIA) registry
Main finding · Respiratory adverse eventsResult — go to the resultAdjusted relative risk 0.41 95% CI 0.19–0.62Authors' conclusion
Overall, SAD use during induction of anaesthesia was associated with a lower risk of adverse respiratory events in children with airway hyperresponsiveness.
Study context
- Population
- Children aged <18 yr undergoing GA with active or recent (within 14 days) upper respiratory tract infection, asthma exacerbation, or household smoking exposure; 12 tertiary-care institutions, J-PEDIA registry, July 2022–February 2025of 27,844 encounters
- Participants
- 4,878 children
- Exposure
- SAD vs Tracheal intubation
- SADn = 1,873
- Tracheal intubationn = 3,005reference
- Outcome
- Occurrence of respiratory adverse events
Methodological detailsmulticentre, propensity score-based inverse probability of treatment weighting, registry
- Multicentre
- Propensity score-based inverse probability of treatment weighting
- Registry
Main finding
Respiratory adverse events
Adjusted relative risk
0.41
95% CI 0.19–0.62
P < 0.001
SAD vs Tracheal intubation
aRR 0.41 (95% CI 0.19–0.62); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aRR (95% CI) | P value | |
|---|---|---|---|
| Airway management-related adverse events | 0.32 (0.19–0.45) | P < 0.001 | |
| Severe oxygen desaturation | 0.47 (0.19–0.75) | P < 0.001 | |
| 0.20.5125Adjusted relative risk (log scale) |
Original publication
Association between supraglottic airway device use and respiratory adverse events during airway management in children with airway hyperresponsiveness: a report from the Japan Paediatric Difficult Airway in Anaesthesia (J-PEDIA) registry. Br J Anaesth. Published 29 September 2026. doi:10. 1016/ j. bja. 2026. 07. 046
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