Paediatric anaesthesia & critical care

Association between supraglottic airway device use and respiratory adverse events during airway management in children with airway hyperresponsiveness: a report from the Japan Paediatric Difficult Airway in Anaesthesia (J-PEDIA) registry

Br J AnaesthPublished Retrospective cohort study

Main finding · Respiratory adverse eventsResult — go to the resultAdjusted relative risk 0.41 95% CI 0.19–0.62

Authors' conclusion

Overall, SAD use during induction of anaesthesia was associated with a lower risk of adverse respiratory events in children with airway hyperresponsiveness.

Study context

Population
Children aged <18 yr undergoing GA with active or recent (within 14 days) upper respiratory tract infection, asthma exacerbation, or household smoking exposure; 12 tertiary-care institutions, J-PEDIA registry, July 2022–February 2025of 27,844 encounters
Participants
4,878 children
Exposure
SAD vs Tracheal intubation
  • SADn = 1,873
  • Tracheal intubationn = 3,005reference
Outcome
Occurrence of respiratory adverse events
Methodological detailsmulticentre, propensity score-based inverse probability of treatment weighting, registry
  • Multicentre
  • Propensity score-based inverse probability of treatment weighting
  • Registry

Main finding

Respiratory adverse events

Adjusted relative risk

0.41

95% CI 0.19–0.62

P < 0.001

SAD vs Tracheal intubation
aRR 0.41 (95% CI 0.19–0.62); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaRR (95% CI)P value
Airway management-related adverse events0.32 (0.19–0.45)P < 0.001
Severe oxygen desaturation0.47 (0.19–0.75)P < 0.001

Original publication

Association between supraglottic airway device use and respiratory adverse events during airway management in children with airway hyperresponsiveness: a report from the Japan Paediatric Difficult Airway in Anaesthesia (J-PEDIA) registry. Br J Anaesth. Published 29 September 2026. doi:10.1016/j.bja.2026.07.046

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