Paediatric anaesthesia & critical care

Videolaryngoscopy and first-attempt tracheal intubation success in neonates and infants: a retrospective cohort study using the Japan Pediatric Difficult Airway in Anesthesia (J-PEDIA) registry

Br J AnaesthPublished Retrospective cohort study

Main findingResult — go to the resultAdjusted relative risk 0.89 95% CI 0.83–0.96

Authors' conclusion

VL use was associated with lower first-attempt tracheal intubation success and a higher risk of desaturation compared with direct laryngoscopy.

Study context

Population
Neonates and infants undergoing tracheal intubation in anaesthesia, Japan Pediatric Difficult Airway in Anesthesia (J-PEDIA) registry, June 2022–February 2025encounters analysed
Participants
3,250 neonates
Exposure
Videolaryngoscopy (VL) vs Direct laryngoscopy
Outcome
First-attempt tracheal intubation success
Methodological detailsmulticentre registry, propensity score-based inverse probability of treatment weighting
  • Multicentre registry
  • Propensity score-based inverse probability of treatment weighting

Main finding

As reported in the abstract

Adjusted relative risk

0.89

95% CI 0.83–0.96

P = 0.001

VL vs Direct laryngoscopy
adjusted RR 0.89 (95% CI 0.83–0.96); P = 0.001

Observational data: associations, not effects.

Secondary outcomes

Outcomeβ (95% CI)P value
Percentage of glottic opening score17.8 (9.5–26.1)P < 0.001

Safety

OutcomeAdjusted RR (95% CI)P value
DesaturationInverse probability of treatment weighting2.18 (1.57–2.79)P < 0.001

Respiratory adverse events

Incidence similar between the groups
adjusted risk ratio −0.09, 95% CI −0.012 to 0.0097, P=0.86
  • Inverse probability of treatment weighting

Original publication

Videolaryngoscopy and first-attempt tracheal intubation success in neonates and infants: a retrospective cohort study using the Japan Pediatric Difficult Airway in Anesthesia (J-PEDIA) registry. Br J Anaesth. Published 23 September 2026. doi:10.1016/j.bja.2026.07.070

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