ICU sedation, delirium & recovery

Interpretable machine learning models for predicting venous thromboembolism in the intensive care unit: an analysis based on data from 207 centers

Crit CarePublished Prediction model development study

Authors' conclusion

ML models can be a reliable tool for predicting VTE in critically ill patients.

Study context

Population
Critically ill ICU patients, eICU Collaborative Research Database1,647 (1.5%) had venous thromboembolism (VTE)
Participants
109,044 patients
Exposure
Random forest vs XGBoost vs support vector machine models
Outcome
VTE during ICU hospitalization (model prediction performance)
Methodological detailsretrospective database analysis, machine learning, fivefold cross-validation, multicentre database (eICU Collaborative Research Database version 2.0)
  • Retrospective database analysis
  • Machine learning
  • Fivefold cross-validation
  • Multicentre database (eICU Collaborative Research Database version 2.0)

Main finding

As reported in the abstract

Model performance for predicting VTE
GroupAUCAccuracyKappaPrecisionF1 scoreSensitivitySpecificity
Random Forest0.93780.99580.83710.90950.83930.77910.9989

Random Forest

AUC0.9378
Accuracy0.9958
Kappa0.8371
Precision0.9095
F1 score0.8393
Sensitivity0.7791
Specificity0.9989

Observational data: associations, not effects.

Original publication

Interpretable machine learning models for predicting venous thromboembolism in the intensive care unit: an analysis based on data from 207 centers. Crit Care. Published 24 October 2023. doi:10.1186/s13054-023-04683-4

Composed by AI from the published abstract and checked against it. How Briefs are made →

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