Intra-articular corticosteroid injections versus platelet-rich plasma as a treatment for cervical facetogenic pain: a randomized clinical trial
Authors' conclusion
Both platelet-rich plasma and corticosteroid injections induced similar improvements in cervical facetogenic pain intensity (1 month post) and self-rated disability (3 and 6 months post).
Study context
- Population
- Patients with cervical facetogenic pain
- Participants
- 40 patients
- Comparison
- Platelet-rich plasma vs Corticosteroid
- Primary endpoint
- Cervical facetogenic pain intensity (NRS)
- Follow-up
- 6-month period post injection
Methodological detailssingle-site, double-blind, Outcomes collected via telephone at 1, 3, and 6 months
- Single-site
- Double-blind
- Outcomes collected via telephone at 1, 3, and 6 months
Primary result
As reported in the abstract
Pain intensity (NRS) · 6 months
- Similar effects in both groups; non-significant group-by-time interaction
- p>0.05
- Both groups significant decrease vs baseline at 1 month; PRP group also clinically significant decrease
- p=0.02
Further findings
Pain self-efficacy · 1 month
- Significant interaction; larger increase with PRP vs corticosteroid
- P = 0.04
Self-rated disability · 3 and 6 months
- No significant interaction; significant reductions vs baseline in both groups
- P < 0.01
Safety
Adverse events
- No significant differences between groups
Procedural pain
- Significantly less procedural pain with PRP
- P = 0.02
Original publication
Intra-articular corticosteroid injections versus platelet-rich plasma as a treatment for cervical facetogenic pain: a randomized clinical trial. Reg Anesth Pain Med. Published 14 November 2024. doi:10.
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