Neuroanesthesia & neurocritical care

Intradural extramedullary tumor location in the axial view affects the alert timing of intraoperative neurophysiologic monitoring

J Clin Monit ComputPublished Retrospective cohort study

Authors' conclusion

Alert is probably triggered during tumor resection for anterolaterally located tumors. Alerts during tumor resection procedures were more likely to be rescued than other procedures in IDEM tumor surgery.

Study context

Population
Patients with intradural extramedullary (IDEM) tumors undergoing surgery with intraoperative neurophysiologic monitoring (IONM), January 2014–March 2021
Participants
39 patients
Outcome
Factors affecting alerts of IONM in IDEM tumor surgery
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Monitoring accuracy of IONM alerts
False-positive cases
11
True-negative cases
16
True-positive cases
1
False-negative cases
1
Sensitivity
50%
Specificity
59%
PPV
8%
NPV
94%

Observational data: associations, not effects.

Further findings

Alert timing by axial tumor location (22 alert cases)

Anterolateral tumors: alerts triggered during tumor resection, significant difference
P = 0.02

Rescue after alerts during tumor resection

Alerts during tumor resection
15
Waveform improvement by intervention (rescue cases)
9 (60%)

Original publication

Intradural extramedullary tumor location in the axial view affects the alert timing of intraoperative neurophysiologic monitoring. J Clin Monit Comput. Published 13 January 2023. doi:10.1007/s10877-022-00971-6

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