Neuroanesthesia & neurocritical care

Utility of desflurane as an anesthetic in motor-evoked potentials in spine surgery and the facilitating effect in tetanic stimulation of bilateral median nerves

J Clin Monit ComputPublished Prospective observational study

Authors' conclusion

However, bilateral median nerve tetanic stimulation can effectively augment MEPs safely under general anesthesia with high-concentration desflurane in patients who undergo spinal surgery.

Study context

Population
Patients scheduled for lumbar surgery under GA with end-tidal 4% desflurane and remifentanil, 2018–2020
Participants
46 patients
Exposure
Post-tetanic motor-evoked potential (MEP) vs conventional MEP under 4% desflurane
Outcome
Reliability of MEP monitoring (recording success rate) and MEP amplitude augmentation by tetanic stimulation
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Average MEP recording success rate

Observational data: associations, not effects.

Further findings

OutcomeP value
MEP amplitudep-MEPm vs c-MEP · significantly higher in all musclesP < 0.05

MEP amplitude

p-MEPt amplitudes not significantly different from conventional MEP (c-MEP)

MEP success rates for gastrocnemius and quadriceps

Inadequate

Original publication

Utility of desflurane as an anesthetic in motor-evoked potentials in spine surgery and the facilitating effect in tetanic stimulation of bilateral median nerves. J Clin Monit Comput. Published 2 November 2023. doi:10.1007/s10877-023-01096-0

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