Pediatric anesthesia & critical care

Intranasal dexmedetomidine sedation for paediatric MRI by radiology personnel: A retrospective observational study

Eur J AnaesthesiolPublished Retrospective observational study

Authors' conclusion

Intranasal dexmedetomidine sedation without immediate presence of anaesthesia personnel appears to be well tolerated and associated with minimal interference on MRI image quality.

Study context

Population
Children 0 to 12 years, ASA 1 or 2, HR within age-appropriate limit, undergoing MRI at a tertiary care paediatric hospital
Participants
1,091 MRIs
Outcome
Changes in haemodynamic and respiratory data before vs after intranasal dexmedetomidine, incidence of critical events, rate of successful MRI scans
Methodological detailssingle institution, Retrospectively registered, Sedation by radiology personnel without immediate presence of anaesthesia personnel
  • Single institution
  • Retrospectively registered
  • Sedation by radiology personnel without immediate presence of anaesthesia personnel

Main finding

As reported in the abstract

Successful MRI scans

Success rate

93%

95% CI 91 to 94%

Observational data: associations, not effects.

Safety

Major critical events

No major critical events recorded

Minor issues

Total incidence of minor issues
0.2% (95% CI 0 to 0.7%)

Heart rate under preset minimal limit after dexmedetomidine

Children with heart rate under preset minimal limit (n)
5
Incidence
0.4% (95% CI 0.1 to 0.9%)

Heart rate and MAP

Significant decreases in heart rate and MAP after dexmedetomidine, within acceptable limits not requiring intervention

Original publication

Intranasal dexmedetomidine sedation for paediatric MRI by radiology personnel: A retrospective observational study. Eur J Anaesthesiol. Published 22 December 2022. doi:10.1097/eja.0000000000001786

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