Perioperative medicine & outcomes
Intraoperative renal desaturation and postoperative acute kidney injury in older patients undergoing liver resection: A prospective cohort study
Main findingResult — go to the resultAdjusted odds ratio 3.41 95% CI 1.12–10.36Authors' conclusion
Intraoperative renal desaturation occurred in >40% in our sample of older patients undergoing liver resection and was associated with increased risk of AKI.
Study context
- Population
- Older patients (≥ 60 years) undergoing open hepatectomy, 2 tertiary hospitals in China, September 2020 to October 2021
- Participants
- 157 patients
- Exposure
- Intraoperative renal desaturation vs no renal desaturation
- Renal desaturationn = 70
- No renal desaturationn = 87reference
- Outcome
- Postoperative AKI (KDIGO serum creatinine criteria)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Adjusted odds ratio
3.41
95% CI 1.12–10.36
P = 0.031
Events by group
Renal desaturation vs No renal desaturation
aOR 3.41 (95% CI 1.12–10.36); P = 0.031
Observational data: associations, not effects.
Further findings
| Outcome | Renal desaturation |
|---|---|
| Predictive performance for AKI | |
| Sensitivity | 69.6% |
| Specificity | 59.7% |
- Predictive performance for acute kidney injury (AKI): Hypotension alone sensitivity 65.2% · specificity 33.6%
- Predictive performance for AKI: Hypotension + renal desaturation sensitivity 95.7% · specificity 26.9%
Incidence of renal desaturation
- Renal desaturation occurred in 70 of 157 patients
Original publication
Intraoperative renal desaturation and postoperative acute kidney injury in older patients undergoing liver resection: A prospective cohort study. J Clin Anesth. Published 9 March 2023. doi:10.
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