Intrathecal fentanyl and intraoperative pain during fetoscopic laser photocoagulation: a single-center retrospective cohort study (2020–2025)
Main finding · Intraoperative painResult — go to the resultOdds ratio 0.33 95% CI 0.15–0.71Authors' conclusion
Intrathecal fentanyl was associated with reduced intraoperative pain during fetoscopic laser photocoagulation without an increase in adverse events.
Study context
- Population
- Patients undergoing fetoscopic laser photocoagulation under spinal anesthesia, single centre
- Participants
- 172 patients
- Exposure
- Intrathecal fentanyl vs no intrathecal fentanyl with spinal anesthesia
- Outcome
- Intraoperative pain (patient-reported)
Methodological detailssingle-centre, multivariable logistic regression
- Single-centre
- Multivariable logistic regression
Main finding
Intraoperative pain
Odds ratio
0.33
95% CI 0.15–0.71
P = 0.005
By group
Intrathecal fentanyl vs No intrathecal fentanyl
OR 0.33 (95% CI 0.15–0.71); P = 0.005
As reported in the abstract
Observational data: associations, not effects.
Safety
Maternal and fetal adverse events
- Did not differ between the groups
Original publication
Intrathecal fentanyl and intraoperative pain during fetoscopic laser photocoagulation: a single-center retrospective cohort study (2020–2025). Int J Obstet Anesth. Published 19 May 2026. doi:10.
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